Less than five percent of people who received the Moderna vaccine reported “Grade 3” pain, which is defined either by pain that prevents a person from completing normal daily activities, or indicates a pain reliever is needed to treat symptoms. Pain was more common after the second dose for recipients of the Moderna vaccine, but slightly less common after the second dose of the Pfizer/BioNTech vaccine. After the first dose of either a Moderna or Pfizer/BioNTech vaccine, just over 70 percent of older people reported pain in their arms, and just over 80 percent of younger people reported pain. Pain at the injection site is the most common side effect, according to the CDC report. The CDC's dataset is broken down by age and shows that older people tend to report fewer side effects than younger people.
MODERNA SIDE EFFECT PROFILE TRIAL
The data come from electronic diaries that clinical trial volunteers kept for seven days after each injection in order to record side effects. Now the Centers for Disease Control and Prevention has released data about how often people experienced side effects after the Pfizer/BioNTech and Moderna vaccines. Wu reported for the Atlanticin February, the second dose of a vaccine can prompt surprisingly strong side effects like fever, chills and fatigue because the immune system is ready to use the skills it learned after the first dose. As the vaccine rollout continues across America, people are rolling up their sleeves-and bracing for side effects, especially after the second dose of the two-part vaccines developed by Moderna and Pfizer/BioNTech.
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